Relationship between CD4+ count, serum inflammatory cytokines, and oral melanotic hyperpigmentation in newly diagnosed HIV seropositive patients: a nested case control study Oral Surgery, Oral Medicine, Oral Pathology and Oral Radiology Perioral Pigmentation One Area. Many Diagnoses. Dark skin around the mouth is one of the most common concerns I see in my OPD but it is never just tanning. Understanding Hyperpigmentation: Causes and Effective Treatments Nima Skin Institute Smoker's melanosis Wikipedia Oral hyperpigmentation Clinical Advisor Lip pigmentation