The methionine cycle and transsulfuration pathway. Notes: Glutathione Download Scientific Diagram Homocysteine and methionine are key amino acids with a vital connection to glutathione one of your body's most important substances! Methionine is abundant in many foods, so protein isn't the culprit, Physiological Roles of Plant Methionine Sulfoxide Reductases in Redox Homeostasis and Signaling Fat burning is not always the problem. Sometimes the issue is detox capacity. When you move into a carnivore or animal based diet, the body relies heavily on a pathway called transsulfuration. GLUTATHIONEtrying to learn more about it ** **The Methylation Cycle: ** After the methyl group gets transferred from L Methylfolate to the enzyme MTRR it is attached to "naked" B12 and this produces S Adenosylmethionine Deficiency and Brain Accumulation of S Adenosylhomocysteine in Thioacetamide Induced Acute Liver Failure