Dressing a Central Line Properly Maimonides Emergency Medicine Residency How to Change the Dressing of Your Peripherally Inserted Central Catheter (PICC) Central Line Dressing Change Education 13. A nurse is changing the central line dressing of a client receiving parenteral nutrition (PN) and notes that there are redness and drainage at the insertion site. The nurse next assesses Central Line Dressing Change Central lines are at a high risk of serious infection. Proper central line care is a key to preventing these central line associated bloodstream infections called Documentation