Oral Mucosal Melanosis IntechOpen Pigmented Lesions of the Oral Mucosa Pocket Dentistry Melanotic macule. Benign. Dark spot on labia (or lip). Analogous to lentigo simplex. Hyperpigmented basal keratinocytes & dermal melanophages. Slight in single basal melanocytes; NO nests. More info like this in Mucosal melanocytic macules Spot the Dot! Growths on the lips are not too common. Clinically, this was consistent with a labial melanotic macule (aka freckle on the lip). These are benign growths which can be Figure 9 from Pigmented lesions of the oral cavity: review, differential diagnosis, and case presentations. Semantic Scholar