Frontiers FOXO4 DRI regulates endothelial cell senescence via the P53 signaling pathway A biological miracle is happening in anti aging where the body takes out the trash. The peptide reduced frailty markers by 50% in aged mice, inducing apoptosis (death) only in damaged cells. It Targeted Apoptosis of Senescent Cells Restores Tissue Homeostasis in Response to Chemotoxicity and Aging: Cell The disordered p53 transactivation domain is the target of FOXO4 and the senolytic compound FOXO4 DRI Nature Communications FOXO4 DRI 10MG Raw Amino Peptide inhibitors targeting FOXO4 p53 interactions and inducing senescent cancer cell specific apoptosis bioRxiv