How SubQ Injections Like B12 and NAD+ Fit Your Routine Olympia Pharmaceuticals B12 vitamin Store How to Perform a Subcutaneous Injection of Vitamin B12 Learn how to administer your own SubQ (subcutaneous) injections at home with confidence. Our step by step guide covers everything you need to know, from preparing your supplies to safely injecting the medication. Our Best Vitamin B12 Injection Sites? ThinWorks Injection Techniques: Injection Routes & Angles Intradermal (ID) 1015 just under the skin (dermis) Subcutaneous (SC) 45 into fat Intravenous (IV) 25 Subcutaneous (SC) and Intramuscular (IM) Injections Must Knows for Subcutaneous administration: Pinch skin with non dominant hand and hold syringe with dominant hand Always inject: 2 inches away from umbilicus (for abdomen) 3 inches