Mast Cells British Society for Immunology Mast cells are hypersensitive immune cells that release histamine and other inflammatory mediatorsoften in response to oxidative stress, environmental toxins, and immune imbalance. Many patients with MCAS have low levels of glutathione. AAAAI Mast Cell Disorders Committee Work Group Report: Mast cell activation syndrome (MCAS) diagnosis and management Journal of Allergy and Clinical Immunology Frontiers Manipulations of Glutathione Metabolism Modulate IP3 Mediated Store Operated Ca2+ Entry on Astroglioma Cell Line The Importance of Glutathione in Health and Healing Dr. Todd Maderis Glutamate triggers the expression of functional ionotropic and metabotropic glutamate receptors in mast cells Cellular & Molecular Immunology