Mitochondrial dysfunction caused by fatty acids and acylcarnitines Download Scientific Diagram Combined metabolic activators to treat mitochondrial dysfunction Mitochondrial dysfunction is a common feature of many human diseases and is emerging as a therapeutic target. Systems biology and multiomics approaches have revealed that Frontiers Dietary supplementation with L carnitine elevates intracellular carnitine levels and affects gene expression of SLC25A20 and COX4I1, as well as non mitochondrial respiration of bovine blood cells during systemic immune challenge Involvement of impaired carnitine induced fatty acid oxidation in experimental and human diabetic kidney disease An overview of the carnitine system in the mitochondria. OCTN2 mediates Download Scientific Diagram Role of carnitine in disease Nutrition & Metabolism Springer Nature Link