Which is better for detoxification, NAC or glutathione? Glutathione vs. NAC: Which Antioxidant Is Best for Your Liver? Life Extension L Glutathione VS NAC: Differences, Similarities, and Uses NAC is one of those supplements that I always have on hand. It's impressive how broadly supportive NAC is. One time I was taking NAC 500 mg every day for about two I'm taking NAC and glutathione as per my OAT and other testing says I need. Yet it makes me depressed. Anyone know why ? NAC vs Glutathione: Which Antioxidant Is Right for You? Momentous