A 48 hour fast can turn standard Paracetamol into acute liver failure. Fasting depletes Glutathione, leaving the liver defenseless against toxic NAPQI. Review the latest guidelines on BMJ Best Practice: https: bestpractice.bmj.com topics en us 1010 Pyrroloquinoline quinone influences intracellular alpha synuclein aggregates Experimental Results Cambridge Core the Master Antioxidant: What Glutathione Injections Can Do for Your Body Depletion of hepatic glutathione and selective protein oxidation and inhibition of lipogenesis Glutathione accelerates the cell cycle and cellular reprogramming in plant regeneration: Developmental Cell Pyrroloquinoline Quinone Is More Than an Antioxidant: A Vitamin like Accessory Factor Important in Health and Disease Prevention