Sulforaphane boosts our natural cellular defenses. It does this by activating Nrf2, our body's primary detoxification, anti inflammatory, and antioxidant pathway. Nrf2 turns on phase 2 detoxification enzymes, helping us deal with daily Glutathione: An Old and Small Molecule with Great Functions and New Applications in the Brain and in Alzheimer's Disease Mohamed Haddad, Vincent Herv, Mohamed Rafet Ben Khedher, Jean Michel Rabanel, Charles Ramassamy, Nrf2 knockdown prevents NFT dependent elevation of glutathione levels. Download Scientific Diagram Multifaceted Roles of Glutathione and Glutathione Based Systems in Carcinogenesis and Anticancer Drug Resistance Elie Hatem, Nadine El Banna, Meng Er Huang, 2017 Nrf2 Regulates Basal Glutathione Production in Astrocytes Coordinate Regulation of Glutathione Biosynthesis and Release by Nrf2 Expressing Glia Potently Protects Neurons from Oxidative Stress Journal of Neuroscience