Mast cells are hypersensitive immune cells that release histamine and other inflammatory mediatorsoften in response to oxidative stress, environmental toxins, and immune imbalance. Many patients with MCAS have low levels of glutathione. The impact of glutathione metabolism in autism spectrum disorder ScienceDirect Glutathione conjugates of the mercapturic acid pathway and guanine adduct as biomarkers of exposure to CEES, a sulfur mustard analog Analytical and Bioanalytical Chemistry Springer Nature Link Glutathione Mediated Conjugation of Anticancer Drugs Encyclopedia MDPI What is MCAS? Aspen Integrative Medical Center Differentiating Changes in Glutathione Levels from Cytotoxic Events Using Multiplexed Assays