Translating the basic knowledge of mitochondrial functions to metabolic therapy: role of L carnitine Translational Research Hepatic Carnitine Palmitoyltransferase (CPT) System: Gateway to Fatty Acid Oxidation Long chain fatty acids cannot directly cross the inner mitochondrial membrane. The hepatic carnitine shuttle system, led by CPT I and transport of fatty acids PPTX Functional differences between l and d carnitine in metabolic regulation evaluated using a low carnitine Nile tilapia model British Journal of Nutrition Cambridge Core Short Note On Carnitine Shuttle: Fatty acids are oxidized in mitochondria, and synthesized in the cytoplasm. Long chain fatty acids must form an active intermediate, fatty acyl CoA, before being oxidized inside mitochondria. Catherine Frontiers Carnitine Traffic in Cells. Link With Cancer