The inhibition of tamoxifen on UGT2B gene expression and enzyme activity in rat liver contribute to the estrogen homeostasis dysregulation BMC Pharmacology and Toxicology Springer Nature Link Estrogen: How It Is Made and How We Get Rid of It Glutathione is often called the master antioxidant But it's actually regulated by melatonin (PMID: 20868358) Melatonin has been seen to have 10x the antioxidant capacity than glutathione Besides sleep, melatonin also regulates 2024 Precision Analytical Inc. Targeting estrogen regulated system xc promotes ferroptosis and endocrine sensitivity of ER+ breast cancer Cell Death & Disease 10 Amazing Glutathione Benefits for Your Body and Health Dr. Tanya Lee, H.BSc., N.D Naturopathic Doctor in Toronto