A cross sectional study of physiologic volar melanotic macules: Demographic, historical, clinical, and dermatoscopic features of a common yet neglected pigmentary variant in individuals with skin of color Journal of the American Cafe au Lait Spots (Macules): Background, Pathophysiology, Etiology Labial Lentigo (labial melanotic macule) Cancer Therapy Advisor Spotty lips. These are labial melanotic macules, kinda like freckles on the lips. They are mostly due to age and sun exposure, but sometimes they run in families and are associated with Oral Melanotic Macule: Symptoms and Treatment Skinsight Pigmented Oral Lesions: Clues to Identifying the Potentially Malignant Consultant360