MTHFR Gene and Glutathione Connection Explained Converging Evolutionary, Environmental and Clinical Ideas on Folate Metabolism The detox gene (MTHFR) is rendered inactive when your diet is high in meat. Our diet should be 80% plant based or higher. MTHFR Why is there so much interest in this gene? [JULY 2020] MTHFR gene mutation detox symptoms and treatment MTHFR Gene Explained: C677T and A1298C Variants, Testing, and Solutions