Glutathione specific gammaglutamylcyclotransferase 1 (CHAC1) increases kidney disease risk by modulating ferroptosis Science Translational Medicine WhyScience #Day33: Genome wide studies have uncovered >1,000 loci linked to kidney function, but pinpointing causal genes remains a hurdle. In our new @SciTransMed paper, we integrated human multi omics and mouse models to Glutathione S transferase Pi monoclonal antibody (USal hGST Pi McAb 1) Enzo Glutathione specific gammaglutamylcyclotransferase 1 (CHAC1) increases kidney disease risk by modulating ferroptosis Science Translational Medicine Downregulation of Glutathione Biosynthesis Contributes to Oxidative Stress and Liver Dysfunction in Acute Kidney Injury Shang 2016 Oxidative Medicine and Cellular Longevity Wiley Online Library Figure 2 from The role of glutathione S transferase P in signaling pathways and S glutathionylation in cancer. Semantic Scholar
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