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paracetamol and glutathione depletion Frontiers
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paracetamol and glutathione depletion Frontiers
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Multiscale modelling approach combining a kinetic model of glutathione metabolism with PBPK models of paracetamol and the potential glutathione depletion biomarkers ophthalmic acid and 5 oxoproline in humans and rats Integrative Biology (RSC Liver injury induced by paracetamol and challenges associated with intentional and unintentional use Longterm adverse effects of paracetamol a review McCrae 2018 British Journal of Clinical Pharmacology Wiley Online Library A study published in Gastroenterology describes a new mitochondrial mediator in the hepatotoxicity induced by paracetamol. Institute of Biomedical Research of Barcelona Can paracetamol (acetaminophen) be administered to patients with liver impairment? Hayward 2016 British Journal of Clinical Pharmacology Wiley Online Library Acetaminophen Pathway (toxic doses), Pharmacokinetics
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paracetamol and glutathione depletion Frontiers
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