Glucose 6 Phosphate Dehydrogenase Deficiency Oncohema Key Pentose Phosphate Pathway made simple. This pathway has two major jobs: Generate NADPH Produce ribose 5 phosphate NADPH protects cells from oxidative stress and supports fatty acid, cholesterol, steroid, nitric oxide, and respiratory burst British Journal of Haematology Wiley Online Library Mini MCAT passage: Pentose phosphate pathway and G6DP deficiency (practice) Khan Academy PeerJ The research progress on the role of glucose 6 phosphate dehydrogenase in immune regulation Clinical associations and potential cellular mechanisms linking G6PD deficiency and atherosclerotic cardiovascular disease npj Metabolic Health and Disease