You've started supporting healthy estrogen balance and detox You're using things like DIM, glutathione and or calcium D glucarate. Maybe you've added liver focused herbs supplements or increased sauna time* But Now, you're no better at Codeage Liposomal Glutathione, Phospholipid, Non GMO Sunflower Oil Repression of adenosine triphosphatebinding cassette transporter ABCG2 by estrogen increases intracellular glutathione in brain endothelial cells following ischemic reperfusion injury ScienceDirect High Estrogen in Young Women: Top Causes, Health Risks, and How to Sup Seeking Health The inhibition of tamoxifen on UGT2B gene expression and enzyme activity in rat liver contribute to the estrogen homeostasis dysregulation BMC Pharmacology and Toxicology Springer Nature Link Estrogen Carcinogenesis in Breast Cancer New England Journal of Medicine