Pseudomelanosis coli Libre Pathology Benign Discoloration Poses Questions “Melanosis” in the small and large intestine Melanosis coli is dark brown black pigmentation of colorectal mucosa associated with chronic use of laxatives containing anthraquinone. Examples of such laxatives include senna and rhubarb derivatives. Clinical Importance: There is no association ICD 10 CM TRAINING July 16, 2013 “Melanosis” in the small and large intestine
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